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VIP (Vasoactive Intestinal Peptide) – Multifunctional Neuropeptide for Research

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide originally isolated from the porcine intestine. It functions as both a neurotransmitter and a hormone, playing diverse roles across multiple physiological systems. VIP exerts its effects primarily through two G-protein-coupled receptors: VPAC1 and VPAC2.

Known for its potent vasodilatory, anti-inflammatory, and immunomodulatory properties, VIP is a key subject of research in respiratory health, neuroprotection, gastrointestinal function, and immune regulation.

Key Research Areas & Potential Effects

• Respiratory & Pulmonary Support: Acts as a powerful bronchodilator and vasodilator. Studied for potential applications in conditions involving airway inflammation, pulmonary hypertension, and chronic respiratory diseases due to its ability to relax bronchial smooth muscle and modulate local immune responses.
• Anti-Inflammatory & Immunomodulatory: Exhibits strong anti-inflammatory effects by suppressing pro-inflammatory cytokines (e.g., TNF-α, IL-6) and shifting immune balance. Researched in models of autoimmune and inflammatory conditions such as arthritis and colitis.
• Neuroprotective & Neurological Effects: Supports brain health, potentially influencing mood, anxiety, and neuroinflammation through effects on neuronal signaling and glial cells.
• Gastrointestinal & Systemic Functions: Promotes smooth muscle relaxation, stimulates secretion in the digestive tract, and contributes to vasodilation and cardiovascular regulation.

VIP’s broad receptor distribution makes it a versatile compound for investigating integrative physiology, inflammation resolution, and peptide-based therapeutics.

At Orlando Biogenics, we offer high-purity Vasoactive Intestinal Peptide (VIP) for laboratory and scientific research. Our product is produced under strict quality controls to support reliable experimentation in immunology, pulmonology, and neuroscience.

For Research Use Only. This product is sold strictly for in vitro and in vivo laboratory research purposes only. It is not intended for human consumption, medical use, diagnostic purposes, or any form of self-administration. Orlando Biogenics makes no claims regarding the therapeutic or medical efficacy of VIP. All research involving this compound must be conducted in accordance with applicable local, state, and federal regulations.

Disclaimer: The information provided on this page is for educational and research purposes only and is not intended as medical advice. VIP is a research peptide with a generally favorable safety profile in controlled studies, but systemic administration may cause vasodilatory effects (e.g., flushing, hypotension) or other responses depending on dosage and model. Long-term safety data in humans remain limited. Always consult with a qualified healthcare professional or institutional review board before considering any use of research peptides. Orlando Biogenics assumes no liability for the misuse of this product.